Table 14
Birth Defects by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2005-2019,
Cases Diagnosed within One Year from Birth

Birth Defects

Diagnostic Grouping2005
to
2019		20052006200720082009201020112012201320142015
to
2019		20152016201720182019
A Central Nervous System (All) 8,217 560 580 518 507 457 443 454 480 532 619 3,067 624 769 534 537 603
  A01 Anencephalus 169 12 14 7 18 15 10 15 12 16 11 39 10 8 6 7 8
  A02 Spina Bifida w/o Anencephaly 765 67 70 62 67 41 57 50 50 41 46 214 46 39 50 35 44
  A03 Hydrocephalus w/o Spina Bifida 1,495 142 135 140 127 112 97 92 88 81 85 396 79 111 62 66 78
  A04 Encephalocele 182 22 13 14 11 10 6 9 14 13 9 61 20 15 6 11 9
  A05 Microcephalus 2,282 135 148 141 100 107 119 122 109 163 185 953 176 220 141 201 215
  A06 Holoprosencephaly --- --- --- --- --- --- --- --- --- --- --- --- --- 9 5 6 5
  A99 Other CNS Anomalies 4,499 255 280 243 251 227 206 222 280 259 346 1,930 416 536 342 295 341
B Eye (All) 5,680 377 321 316 327 300 290 333 319 462 514 2,121 461 398 307 455 500
  B01 Anopthalmos
/Micropthalmos 		274 26 24 23 22 14 18 19 13 22 11 82 13 21 17 18 13
  B02 Congenital Cataract 361 38 22 27 31 16 29 30 19 22 14 113 22 26 26 16 23
  B03 Aniridia 52 6 2 4 3 - 4 3 4 3 6 17 2 3 2 3 7
  B99 Other Eye Anomalies 5,309 343 301 283 297 284 262 306 303 438 495 1,997 434 368 281 439 475
C Ear, Face and Neck (All) 4,608 263 204 188 217 170 180 193 197 238 334 2,424 412 530 434 527 521
  C01 Anotia/Microtia 305 15 15 18 19 16 19 24 19 14 11 135 27 29 24 31 24
  C99 Other Ear, Face &
Neck Anomalies 		4,525 259 203 182 211 166 174 187 190 236 333 2,384 403 524 431 514 512
D Heart & Circulatory System (All) 36,702 2,775 2,846 2,499 2,462 2,051 1,970 2,071 2,244 2,218 2,728 12,838 2,251 2,736 2,381 2,534 2,936
  D01 Common Truncus 227 17 18 15 22 7 22 18 18 16 17 57 15 11 8 15 8
  D02 Transposition of Great
Vessels 		693 67 55 41 46 44 48 45 50 45 53 199 48 47 39 30 35
  D03 Tetralogy of Fallot 942 70 75 62 81 49 71 73 64 65 59 273 60 67 43 60 43
  D04 Ventricular Septal Defect 8,008 596 574 529 552 418 440 459 538 467 606 2,829 522 593 507 589 618
  D05 Atrial Septal Defect 20,481 1,246 1,296 1,077 1,174 1,011 957 1,168 1,312 1,231 1,732 8,277 1,377 1,796 1,564 1,592 1,948
  D06 Atrioventricular Septal Defect (Endocardial Cushion Defect) 953 71 81 64 69 56 62 70 71 62 65 282 57 59 64 52 50
  D07 Pulmonary Valve
Atresi& Stenosis 		1,884 179 170 149 138 95 127 112 126 95 122 571 114 124 122 95 116
  D08 Tricuspid Valve
Atresi& Stenosis 		224 23 11 19 22 11 18 17 17 14 19 53 8 8 12 10 15
  D09 Ebstein's Anomaly 127 13 11 8 13 7 9 9 13 9 9 26 9 6 5 5 1
  D10 Aortic Valve Stenosis 391 34 31 31 28 21 20 28 29 21 27 121 28 33 23 17 20
  D11 Hypoplastic Left Heart
Syndrome 		719 64 49 54 48 56 37 44 62 53 51 201 41 44 31 37 48
  D12 Patent Ductus Arteriosis 12,243 971 977 815 829 624 600 727 731 589 983 4,397 764 1,012 843 796 982
  D13 Coarctation of Aorta 1,246 80 95 86 88 56 66 74 95 90 99 417 77 99 87 81 73
  D14 Pulmonary Artery Anomalies 2,967 303 313 256 257 230 204 128 46 43 64 1,123 143 222 167 278 313
  D15 Interrupted Aortic Arch 121 6 12 4 12 11 11 8 14 7 7 29 5 5 1 10 8
  D16 Total Anomalous Pulmonary
Venous Return (or connection) 		222 24 22 8 17 14 17 11 19 17 14 59 14 13 15 8 9
  D17 Double Outlet Right Ventricle 451 31 30 30 27 28 39 25 32 27 34 148 35 31 28 28 26
  D18 Common Ventricel 325 22 23 18 25 14 29 14 29 18 24 109 21 23 18 24 23
  D99 Other Heart &
Circulatory System
Anomalies 		13,320 1,020 1,178 992 930 786 758 701 795 799 985 4,376 836 843 749 928 1,020
E Respiratory System (All) 9,589 748 1,048 872 491 404 474 479 586 566 718 3,203 639 666 548 683 667
  E01 Lung Agenesis/
Hypoplasia 		1,150 96 78 63 75 87 110 74 65 61 109 332 60 86 47 60 79
  E02 Choanal Atresia 315 24 18 16 18 22 23 20 26 30 23 95 20 22 12 19 22
  E99 Other Respiratory
System Anomalies 		8,482 653 975 810 423 312 366 404 522 502 618 2,897 584 588 509 620 596
F Cleft Palate & Cleft Lip 2,867 205 228 205 186 214 170 174 171 181 201 932 224 171 175 201 161
  F01 Cleft Palate 1,716 127 135 131 119 133 103 95 108 124 129 512 127 93 87 106 99
  F02 Cleft Lip w & w/o Cleft Palate 1,662 114 129 109 100 117 111 112 110 93 117 550 127 98 89 133 103
G Upper Alimentary Caanal/
Digestive System (All) 		8,877 682 814 717 687 615 522 521 552 556 586 2,625 476 613 477 495 564
  G01 Esophageal Atresia/
Tracheoesophageal Fistula 		421 43 35 40 29 14 29 29 26 32 28 116 21 19 26 21 29
  G02 Rectal & Large Intestinal
Atresia/Stenosis 		794 62 75 55 54 46 59 59 50 68 52 214 40 52 40 33 49
  G03 Pyloric Stenosis 2,777 195 234 208 239 217 156 156 178 135 186 873 169 219 170 150 165
  G04 Hirshsprung's Disease
(congenital megacolon) 		695 36 38 34 36 24 49 44 37 38 36 323 51 76 59 61 76
  G05 Biliary Atresia 210 12 13 11 14 14 12 18 16 12 8 80 13 20 15 18 14
  G99 Other Upper
Alimentary Canal
/Digestive System Anomalies 		4,798 388 463 411 362 334 261 274 304 326 340 1,335 239 285 222 277 312
H Genital & Urinary Systems 26,338 2,009 2,017 1,815 1,535 1,244 1,223 1,594 1,644 1,812 2,125 9,320 1,775 1,927 1,658 1,869 2,091
  H01 Renal Agenesis/
Hypoplasia 		1,052 72 63 82 84 52 58 55 63 85 89 349 56 78 58 66 91
  H02 Bladder Exstrophy &
Cloacal Exstrophy 		43 6 4 1 3 3 2 1 - 5 3 15 4 3 2 1 5
  H03 Obstructive Genitourinary
Defects 		5,371 330 308 291 280 206 204 275 318 300 441 2,418 419 483 446 522 548
  H04 Hypospadias 5,994 469 327 362 426 343 363 440 357 396 479 2,032 402 454 362 413 401
  H05 Epispadias 172 13 11 6 11 11 4 5 10 13 8 80 10 19 11 14 26
  H99 Other Genital
& Urinary System
Anomalies 		17,635 1,434 1,550 1,343 973 820 796 1,055 1,163 1,262 1,436 5,803 1,133 1,205 1,022 1,134 1,309
I Musculoskeletal System (All) 33,787 2,301 2,501 2,344 1,720 1,440 1,804 1,978 2,429 2,656 2,919 11,695 2,220 2,373 1,898 2,681 2,523
  I01 Upper Limb Reduction
Deformities 		424 28 28 38 38 29 34 32 28 28 31 110 19 32 22 22 15
  I02 Lower Limb Reduction
Deformities 		392 37 35 25 21 32 22 32 34 24 30 100 14 22 22 23 19
  I03a Exomphalos/
Omphalocele 		--- --- --- --- --- --- 23 21 27 16 15 225 21 31 46 83 44
  I03b Gastroschisis --- --- --- --- --- --- 63 55 44 41 53 220 41 56 36 53 34
  I03c Prune Belly Syndrome,
Congenital Hernia of Bladder 		679 82 95 85 72 59 31 20 30 49 34 122 12 23 27 24 36
  I04 Congenital Hip Dislocation 1,713 127 167 108 155 142 126 143 124 98 89 434 93 95 76 69 101
  I05 Diaphragmatic Hernia 558 36 52 42 38 45 41 39 26 28 47 164 34 41 25 30 34
  I99 Other Musculoskeletal
System 		31,033 2,110 2,276 2,171 1,535 1,247 1,599 1,776 2,244 2,491 2,739 10,845 2,093 2,197 1,728 2,475 2,352
J Integument (All) 18,556 629 1,274 499 1,353 1,204 876 1,075 820 1,600 2,249 6,977 1,326 1,364 1,056 1,125 2,106
K Chromosomal Anomalies 4,521 316 324 288 315 296 300 281 313 305 299 1,484 281 314 295 291 303
  K01 Trisomy 13 131 17 8 10 10 9 7 12 10 8 10 30 6 6 9 4 5
  K02 Down Syndrome 2,244 176 183 147 159 141 175 141 156 142 144 680 123 136 161 129 131
  K03 Trisomy 18 234 16 19 15 23 18 11 17 15 15 16 69 25 11 10 13 10
  K04 Chromosome 22q11.2
Deletion Syndrome 		--- --- --- 7 11 6 7 7 9 10 6 64 6 17 8 17 16
  K05 Turner Syndrome 155 10 20 14 10 7 4 5 3 6 9 67 6 15 11 13 22
  K99 Other Chromosomal
Anomalies 		1,914 120 107 122 124 139 113 130 148 149 132 630 123 140 109 126 132
L Other and Unspecified
Birth Defects 		27,187 622 490 392 260 205 1,926 1,872 2,148 2,213 2,611 14,448 2,290 2,376 2,739 3,600 3,443
                                  

Table 14
Birth Defects by Detailed Diagnostic Code Group and Birth Year,
Michigan Resident Children Born in Michigan During 2005-2019,
Cases Diagnosed within One Year from Birth
(Continued)

Other Reportable Conditions

Diagnostic Grouping2005
to
2019		20052006200720082009201020112012201320142015
to
2019		20152016201720182019
M Infectious Conditions
Occurring in the Perinatal
Period 		914 44 51 32 85 68 46 55 81 75 94 283 62 60 46 48 67
  M01 Syphilis 223 14 13 5 28 26 9 8 14 20 30 56 14 15 9 4 14
  M02 Other Infections 677 30 38 27 57 43 37 45 63 51 58 228 49 45 37 44 53
  M03 Zika Virus Disease 17 - - - - - - 2 5 4 6 - - - - - -
N Familial/Congenital
Neoplasms 		227 19 19 20 20 5 10 15 15 15 13 76 20 11 16 13 16
O Endocrine/Metabolic
Disorders 		10,689 575 603 500 603 471 565 558 748 770 918 4,378 831 997 778 828 944
P Diseases of the Blood
& Blood Forming Organs 		5,646 328 310 261 310 252 336 374 370 421 515 2,169 489 498 372 400 410
Q Other Diseases of the
Central and Peripheral
Nervous System 		6,379 434 437 392 379 349 337 423 421 426 542 2,239 455 499 342 503 440
R Other Diseases of the Eye 10,332 850 846 838 787 623 598 666 639 730 756 2,999 674 632 434 649 610
S Hearing Deficiency 12,018 562 534 462 521 454 612 974 1,008 1,103 1,192 4,596 803 1,247 907 940 699
T Other Diseases of the
Heart & Circulatory System 		7,333 433 515 460 483 421 428 435 602 536 563 2,457 496 534 440 493 494
U Other Diseases of the
Gastrointestinal System 		9,085 782 702 674 672 486 568 552 629 638 719 2,663 611 561 455 512 524
V Other Diseases of the
Genital and Urinary Systems 		2,076 62 59 39 37 52 58 62 67 89 127 1,424 173 252 256 353 390
X Other Musculoskeletal
System Diseases 		37 1 3 3 1 4 4 5 4 6 4 2 1 1 - - -
Y Maternal Exposures
Affecting Fetus 		8,778 313 317 205 314 266 310 450 487 528 877 4,711 675 1,149 995 1,061 831
  Y01 Newborn Affected by
Maternal use of Alcohol 		204 20 20 13 5 6 10 9 9 13 16 83 11 20 11 20 21
  Y02 Fetal Alcohol Syndrome --- --- --- --- --- --- --- --- --- --- --- --- --- 11 4 6 9
  Y99 Other Maternal Exposures
Affecting the Fetus 		8,600 293 298 197 310 261 301 435 479 517 863 4,646 669 1,133 985 1,046 813
One or More
Reportable Diagnosis 		 180,145 11,158 11,747 9,938 9,705 8,040 9,694 10,679 11,475 12,956 15,371 69,382 12,593 14,049 12,636 14,543 15,561
                                  

Notes:
Frequencies include all children reported with a birth defect who were born in Michigan and whose mother was a resident at the time of birth. This enables the calculation of birth defect prevalence rates. Birth defect statistics sometimes reflect trends related to data reporting or new testing. See Data Quality Considerations for further details.
Columns do not add to summary group totals, nor column totals, due to cases with multiple diagnosed conditions that cross diagnostic groupings
Conditions are reportable if identified within the first two years of a child's life. The prevalence frequencies in this table represent cases diagnosed within the first year of life.
Prior to October 2015, diagnoses were coded using the 9th revision to the International Classification of Diseases - ICD–9–CM.  (See Birth Defect Groups and ICD–9–CM Diagnosis Codes for the codes used to categorize birth defects.) After October 2015, the Birth Defect registry coded diagnoses using ICD–10–CM. (See Birth Defect Groups and ICD–10–CM Diagnosis Codes for the codes used to categorize birth defects.) Diagnostic Code Groupings used in analysis of birth defects are defined by the Centers for Disease Control.
Source: Michigan Birth Defects Registry, Division for Vital Records & Health Statistics, Michigan Department of Health & Human Services
Reports Processed through May 28, 2022

Last Updated on May 1, 2022