Age-adjusted Opioid Drug Overdoses Mortality Rates by Sex,
White Michigan Residents 2000-2022

Year All Opioids1 Prescription Opioids2 Heroin3 Synthetic Opioids other
than Methadone4
Total Male Female Total Male Female Total Male Female Total Male Female
2000 1.5 ±0.2 2.3 ±0.4 0.7 ±0.2 0.5 ±0.1 0.7 ±0.2 *      0.6 ±0.1 1.1 ±0.3 *   *     *   *    
2001 1.6 ±0.2 2.3 ±0.4 0.9 ±0.2 0.6 ±0.1 0.8 ±0.2 0.4 ±0.2 0.6 ±0.1 1.0 ±0.3 *    *     *     *    
2002 2.1 ±0.3 2.8 ±0.5 1.3 ±0.3 1.2 ±0.2 1.7 ±0.3 0.7 ±0.2 0.4 ±0.1 0.8 ±0.2 *    0.3 ±0.1 *     0.4 ±0.2
2003 2.4 ±0.3 2.9 ±0.5 1.9 ±0.4 1.3 ±0.2 1.4 ±0.3 1.1 ±0.3 0.5 ±0.1 0.8 ±0.2 *    0.4 ±0.1 *     *    
2004 3.3 ±0.3 4.6 ±0.6 2.0 ±0.4 1.9 ±0.2 2.4 ±0.4 1.3 ±0.3 0.8 ±0.1 1.3 ±0.3 *    0.5 ±0.1 0.7 ±0.2 *  
2005 4.7 ±0.4 6.2 ±0.7 3.1 ±0.5 2.6 ±0.3 3.5 ±0.5 1.7 ±0.3 1.2 ±0.2 1.8 ±0.4 0.7 ±0.2 0.9 ±0.2 1.0 ±0.3 0.7 ±0.2
2006 5.9 ±0.5 7.8 ±0.8 4.0 ±0.6 3.2 ±0.3 4.1 ±0.6 2.2 ±0.4 1.3 ±0.2 2.0 ±0.4 0.6 ±0.2 1.7 ±0.2 2.2 ±0.4 1.3 ±0.3
2007 5.2 ±0.5 7.2 ±0.8 3.1 ±0.5 3.4 ±0.4 4.7 ±0.6 2.2 ±0.4 1.0 ±0.2 1.7 ±0.4 *     0.7 ±0.1 0.8 ±0.2 0.6 ±0.2
2008 6.5 ±0.5 8.5 ±0.9 4.6 ±0.6 3.5 ±0.4 4.2 ±0.6 2.8 ±0.5 2.1 ±0.3 3.3 ±0.5 0.9 ±0.3 0.7 ±0.1 0.8 ±0.2 0.6 ±0.2
2009 7.5 ±0.6 10.3 ±1.0 4.7 ±0.6 3.9 ±0.4 5.2 ±0.7 2.5 ±0.4 2.3 ±0.3 3.7 ±0.6 1.0 ±0.3 1.0 ±0.2 0.9 ±0.3 1.0 ±0.3
2010 7.5 ±0.6 10.1 ±1.0 4.9 ±0.6 4.1 ±0.4 5.4 ±0.7 2.8 ±0.5 2.3 ±0.3 3.5 ±0.6 1.1 ±0.3 0.9 ±0.2 1.0 ±0.3 0.9 ±0.2
2011 7.5 ±0.6 10.0 ±1.0 5.1 ±0.7 3.8 ±0.4 4.6 ±0.7 2.9 ±0.5 2.7 ±0.3 4.1 ±0.6 1.2 ±0.3 0.9 ±0.2 0.8 ±0.2 0.9 ±0.3
2012 7.4 ±0.6 9.4 ±0.9 5.3 ±0.7 3.9 ±0.4 4.4 ±0.6 3.4 ±0.6 2.9 ±0.3 4.3 ±0.6 1.3 ±0.3 0.8 ±0.2 0.8 ±0.3 0.7 ±0.2
2013 9.8 ±0.7 12.4 ±1.1 7.2 ±0.8 4.5 ±0.4 5.0 ±0.7 4.0 ±0.6 4.6 ±0.4 6.8 ±0.8 2.2 ±0.4 0.9 ±0.2 0.7 ±0.2 1.0 ±0.3
2014 11.2 ±0.7 14.7 ±1.2 7.7 ±0.9 4.6 ±0.4 5.2 ±0.7 4.0 ±0.6 5.5 ±0.5 8.0 ±0.9 2.9 ±0.5 1.8 ±0.3 2.1 ±0.4 1.5 ±0.4
2015 14.4 ±0.8 19.0 ±1.4 9.7 ±1.0 5.6 ±0.5 6.5 ±0.8 4.8 ±0.7 7.0 ±0.6 10.1 ±1.0 3.8 ±0.6 4.9 ±0.5 6.8 ±0.8 2.9 ±0.5
2016 19.6 ±1.0 26.8 ±1.7 12.3 ±1.1 7.6 ±0.6 9.5 ±1.0 5.7 ±0.7 7.9 ±0.6 11.4 ±1.1 4.3 ±0.6 10.2 ±0.7 14.5 ±1.2 5.8 ±0.8
2017 21.8 ±1.0 28.3 ±1.7 15.2 ±1.2 7.2 ±0.6 7.9 ±0.9 6.5 ±0.8 8.2 ±0.6 11.4 ±1.1 5.0 ±0.7 14.7 ±0.9 20.4 ±1.4 9.0 ±0.9
2018 20.7 ±1.0 27.0 ±1.7 14.2 ±1.2 6.0 ±0.5 7.0 ±0.8 4.9 ±0.7 6.3 ±0.5 8.4 ±0.9 4.2 ±0.6 15.7 ±0.9 20.9 ±1.5 10.4 ±1.0
2019 17.2 ±0.9 23.0 ±1.5 11.3 ±1.1 4.7 ±0.4 5.5 ±0.7 3.8 ±0.6 4.1 ±0.4 5.6 ±0.7 2.7 ±0.5 13.9 ±0.8 19.2 ±1.4 8.5 ±0.9
2020 20.3 ±1.0 27.9 ±1.7 12.4 ±1.1 5.0 ±0.5 6.7 ±0.8 3.3 ±0.5 4.2 ±0.4 5.8 ±0.7 2.5 ±0.5 17.7 ±0.9 24.8 ±1.6 10.4 ±1.0
2021 23.2 ±1.1 31.2 ±1.8 14.8 ±1.2 5.2 ±0.5 6.2 ±0.8 4.2 ±0.6 1.7 ±0.3 2.4 ±0.5 0.9 ±0.3 20.7 ±1.0 28.7 ±1.7 12.4 ±1.1
2022 20.8 ±1.0 28.3 ±1.7 13.0 ±1.2 3.4 ±0.4 4.1 ±0.6 2.8 ±0.5 1.1 ±0.2 1.5 ±0.4 0.7 ±0.2 19.0 ±1.0 26.3 ±1.6 11.3 ±1.1


Rates are per 100,000. Computed by the direct method, using as the standard population the age distribution of the total population of the United States for the year 2000. The true rate lies between the lower and upper bounds of the interval with 95% statistical confidence.

An asterisk (*) indicates that the data do not meet standards of reliability or precision.

Opioid deaths:Summing of categories will result in more than the number of all opioid drug overdoses. Categories of deaths are not exclusive as deaths might involve more than one drug.

1Opioid drug overdoses are those with an underlying cause of death defined by the ICD-10 codes: X40-X44, X60-X64, X85, and Y10-Y14; these overdoses must have a related cause of death of T40.0-T40.4 or T40.6. 2Prescription overdoses available by prescription only, with any of the following ICD-10 codes listed as a related cause of death: T40.2-T40.3. This list includes both prescription opioid pain relievers (e.g., hydrocodone, oxycodone, and morphine) and opioids used to treat addiction (e.g., methadone).

3Heroin overdoses are drug overdoses with related cause death codes T40.1.

4Fentanyl & Other Synthetic Opioid are drug overdoses with related cause of death code T40.4.

Source: 2000-2022 Michigan Death Files, Division for Vital Records and Health Statistics, Michigan Department of Health and Human Services.